Description

Vinblastine Nb-Oxide Maleic Acid Salt is a chemically modified derivative of the potent Vinca alkaloid, vinblastine. This compound is significant for its role as a key intermediate in pharmaceutical research and development, particularly in the synthesis of novel anti-cancer agents and for metabolic studies. It is primarily needed by research institutions, pharmaceutical manufacturers, and biotechnology companies engaged in oncology drug discovery and advanced chemical synthesis.

Application

• Pharmaceutical Intermediate: Critical for the research and synthesis of novel chemotherapeutic agents and prodrugs targeting various cancers.
• Biochemical Research: Used as a reference standard or probe in metabolic pathway studies and mechanism-of-action investigations for Vinca alkaloids.
• Analytical Standard: Serves as a high-purity standard for quality control and analytical method development (e.g., HPLC, LC-MS) in pharmaceutical laboratories.
• Academic Research: Employed in university and institutional labs for studying structure-activity relationships (SAR) and chemical modifications of natural products.
• Process Development: Utilized in scaling up and optimizing synthetic routes for complex pharmaceutical active ingredients (APIs).

Basic Information

Product Name	Vinblastine Nb-Oxide Maleic Acid Salt
CAS No.	947607-87-6
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Vinblastine N-oxide maleate; Vinblastine N-oxide maleic acid salt; 3',4'-Didehydro-4'-deoxy-8'-norvincaleukoblastine N-oxide maleate; Vincaleukoblastine, 3',4'-didehydro-4'-deoxy-8'-nor-, N-oxide, maleate (1:1); Vinblastine N-Oxide (Maleic Acid Salt); Vinblastine Nb-Oxide Maleate Salt
EINECS	Contact for details

Quality Control

Our Vinblastine Nb-Oxide Maleic Acid Salt is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, MS), to ensure it meets the high standards required for pharmaceutical research. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.