Description

2-(Trifluoromethylthio)-Benzeneboronic Acid is a specialized organoboron building block featuring a unique trifluoromethylthio (-SCF₃) substituent. This compound is valued for its role in facilitating the synthesis of complex molecules, particularly through cross-coupling reactions like the Suzuki-Miyaura reaction. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for constructing drug candidates, especially those incorporating the metabolically stable and lipophilic -SCF₃ group.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides where the trifluoromethylthio moiety can enhance biological activity.
• Material Science Research: Serves as a precursor for creating functionalized polymers, liquid crystals, or organic electronic materials.
• Suzuki-Miyaura Cross-Coupling: An essential boronic acid reagent for forming carbon-carbon bonds between aromatic rings in complex molecule assembly.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes.
• Catalyst Ligand Development: Potential building block for novel ligand systems in transition metal catalysis.

Basic Information

Product Name	2-(Trifluoromethylthio)-Benzeneboronic Acid
CAS No.	947533-17-7
Molecular Formula	C₇H₆BF₃O₂S
Molecular Weight	221.99 g/mol
Synonyms	(2-((Trifluoromethyl)thio)phenyl)boronic acid; Benzeneboronic acid, 2-[(trifluoromethyl)thio]-; 2-(Trifluoromethylsulfanyl)benzeneboronic acid; 2-(Trifluoromethylthio)phenylboronic acid; 2-SCF3-Phenylboronic Acid; 2-(Trifluoromethylmercapto)benzeneboronic acid; B-[2-[(Trifluoromethyl)thio]phenyl]boronic acid
EINECS	Contact for details

Quality Control

Our 2-(Trifluoromethylthio)-Benzeneboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your R&D and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.