Description

3-Fluoro-4-(2,2,2-Trifluoro-Ethoxy)-Benzeneboronic Acid is a high-purity boronic acid derivative, a critical building block in modern synthetic chemistry. Its value lies in its role as a key coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for drug discovery and specialty chemical synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing complex fluorinated aromatic systems.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that leverage its unique fluorinated structure.
• Suzuki-Miyaura Cross-Coupling: Serves as a versatile boronic acid coupling partner for palladium-catalyzed reactions to form carbon-carbon bonds.
• Ligand and Catalyst Development: Employed in the creation of novel ligands and organometallic catalysts for asymmetric synthesis.
• Material Science Research: A building block for developing organic electronic materials, such as those used in OLEDs and semiconductors.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes and tags for studying biological processes.

Basic Information

Product Name	3-Fluoro-4-(2,2,2-Trifluoro-Ethoxy)-Benzeneboronic Acid
CAS No.	947533-09-7
Molecular Formula	C8H7BF4O3
Molecular Weight	238.95 g/mol
Synonyms	[4-(2,2,2-Trifluoroethoxy)-3-fluorophenyl]boronic acid; 3-Fluoro-4-(2,2,2-trifluoroethoxy)phenylboronic acid; Benzeneboronic acid, 3-fluoro-4-(2,2,2-trifluoroethoxy)-; 4-(2,2,2-Trifluoroethoxy)-3-fluorobenzeneboronic Acid; 3-Fluoro-4-(trifluoroethoxy)phenylboronic acid; 3-Fluoro-4-(2,2,2-trifluoroethoxy)benzeneboronic acid; CAS 947533-09-7
EINECS	Contact for details

Quality Control

Our 3-Fluoro-4-(2,2,2-Trifluoro-Ethoxy)-Benzeneboronic Acid is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and commercial synthesis. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality systems are designed to meet the stringent requirements of the pharmaceutical and fine chemical industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.