Description

n-(Dicyclohexylphosphino)-2-(2′-Methoxyphenyl)indole is a specialized monodentate phosphine ligand designed for transition metal catalysis. This compound matters for its ability to facilitate challenging cross-coupling and C-H activation reactions, offering chemists a valuable tool for constructing complex molecular architectures. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for synthesizing novel active ingredients and functional molecules.

Application

• As a ligand in palladium-catalyzed cross-coupling reactions, such as Suzuki-Miyaura, Buchwald-Hartwig amination, and Negishi couplings.
• For catalyst development in C-H functionalization processes to create new carbon-carbon and carbon-heteroatom bonds.
• In the synthesis of pharmaceutical intermediates and active pharmaceutical ingredients (APIs) requiring selective transformations.
• For research and development of novel catalytic systems in academic and industrial laboratories.
• In the preparation of specialty chemicals and fine chemicals where high selectivity and yield are critical.
• As a key component in homogeneous catalysis for agrochemical and material science applications.

Basic Information

Product Name	n-(Dicyclohexylphosphino)-2-(2′-Methoxyphenyl)indole
CAS No.	947402-60-0
Molecular Formula	C27H34NOP
Molecular Weight	419.54 g/mol
Synonyms	2-(2-Methoxyphenyl)-1H-indol-1-yl(dicyclohexyl)phosphine; Dicyclohexyl[2-(2-methoxyphenyl)-1H-indol-1-yl]phosphine; n-(Dicyclohexylphosphino)-2-(2'-methoxyphenyl)indole; 1-(Dicyclohexylphosphino)-2-(2-methoxyphenyl)indole; DCPMI; (2-(2-Methoxyphenyl)-1H-indol-1-yl)dicyclohexylphosphine
EINECS	Contact for details

Quality Control

Our n-(Dicyclohexylphosphino)-2-(2′-Methoxyphenyl)indole is manufactured under strict quality protocols to ensure batch-to-batch consistency and high purity for catalytic applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable to support our customers in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. Due to its sensitivity to oxidation, the container should only be opened in an inert environment.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.