Description

1-(Dicyclohexylphosphino)-2-Phenyl-1H-Indole, Min. 98% Npcy Phendole-Phos is a specialized, high-purity organophosphorus ligand designed for advanced catalytic applications. This compound matters because it offers exceptional selectivity and activity in cross-coupling reactions, enabling the efficient synthesis of complex organic molecules. It is primarily needed by R&D chemists and process engineers in the pharmaceutical, agrochemical, and advanced materials industries for developing new active ingredients and fine chemicals.

Application

• Catalyst Ligand in Cross-Coupling Reactions: A key component in Buchwald-Hartwig amination, Suzuki-Miyaura, and other palladium-catalyzed C–N and C–C bond-forming reactions.
• Pharmaceutical Intermediate Synthesis: Enables the efficient and selective construction of complex heterocyclic scaffolds and active pharmaceutical ingredients (APIs).
• Agrochemical Research & Development: Used in the catalytic synthesis of novel herbicides, fungicides, and plant growth regulators.
• Material Science & OLED Development: Facilitates the synthesis of conjugated organic molecules for electronic materials and organic light-emitting diodes (OLEDs).
• Academic & Industrial R&D: A valuable tool for methodology development and exploring new catalytic transformations in laboratory and pilot-scale settings.
• Asymmetric Catalysis: Potential use in chiral ligand libraries for enantioselective synthesis when combined with appropriate metal centers.

Basic Information

Product Name	1-(Dicyclohexylphosphino)-2-Phenyl-1H-Indole, Min. 98% Npcy Phendole-Phos
CAS No.	947402-57-5
Molecular Formula	C30H36NP
Molecular Weight	441.59 g/mol
Synonyms	Npcy Phendole-Phos; 1-(Dicyclohexylphosphino)-2-phenylindole; 2-Phenyl-1-(dicyclohexylphosphino)-1H-indole; Dicyclohexyl(2-phenyl-1H-indol-1-yl)phosphine; Phendole-Phos; Buchwald Ligand; Phosphine Ligand; CataCXium® P (analogous class)
EINECS	Contact for details

Quality Control

Our 1-(Dicyclohexylphosphino)-2-Phenyl-1H-Indole is manufactured under strict quality protocols to ensure batch-to-batch consistency and a minimum purity of 98%. Each lot is characterized by NMR (1H, 13C, 31P) and HPLC analysis to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We adhere to cGMP principles where applicable to support our clients in regulated industry segments.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store the product under an inert atmosphere (argon or nitrogen) at 2-8°C. The material is easily oxidized (store under inert atmosphere) and light-sensitive (store away from light). Allow the sealed container to reach ambient temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	Min. 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.