Description

Carbamic Acid, n-(5-Bromo-4-Methyl-2-Thiazolyl)-, 1,1-Dimethylethyl Ester is a high-purity, advanced pharmaceutical intermediate characterized by its distinct thiazole and carbamate functional groups. This compound matters for its critical role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex heterocyclic scaffolds. Industrial and research chemists need this material for the development of next-generation pharmaceuticals, agrochemicals, and other fine chemical products where precise bromine substitution and steric protection are required.

Application

• Pharmaceutical Intermediate: A crucial precursor in the multi-step synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Research: Serves as a key synthon for developing new herbicides, fungicides, and insecticides that leverage the bioactivity of the thiazole moiety.
• Chemical Biology & Proteomics: Used in the design and synthesis of activity-based probes (ABPs) and molecular tags for studying enzyme function and protein interactions.
• Material Science: Potential monomer or additive for creating specialized polymers with unique electronic or photophysical properties.
• Academic & Contract Research: Essential for medicinal chemistry programs in universities and CROs focused on heterocyclic compound library generation and structure-activity relationship (SAR) studies.

Basic Information

Product Name	Carbamic Acid, n-(5-Bromo-4-Methyl-2-Thiazolyl)-, 1,1-Dimethylethyl Ester
CAS No.	947179-42-2
Molecular Formula	C9H13BrN2O2S
Molecular Weight	293.18 g/mol
Synonyms	tert-Butyl (5-bromo-4-methylthiazol-2-yl)carbamate; N-Boc-5-Bromo-4-methyl-2-aminothiazole; 2-((tert-Butoxycarbonyl)amino)-5-bromo-4-methylthiazole; 5-Bromo-4-methyl-2-((tert-butoxycarbonyl)amino)thiazole; (5-Bromo-4-methyl-1,3-thiazol-2-yl)carbamic acid tert-butyl ester; BOC-5-Bromo-4-methyl-2-aminothiazole; 947179-42-2; tert-Butyl N-(5-bromo-4-methyl-1,3-thiazol-2-yl)carbamate
EINECS	Contact for details

Quality Control

Our Carbamic Acid, n-(5-Bromo-4-Methyl-2-Thiazolyl)-, 1,1-Dimethylethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for pharmaceutical R&D and scale-up. Certificates of Analysis (COA) with complete chromatographic data and spectroscopic profiles are provided for every shipment, ensuring full traceability and compliance with your internal quality protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.