Description

n-(2-Aminophenyl)-2-Methylbutanamide (Saltdata: Free) is a specialized organic compound featuring both an amide and a primary aromatic amine functional group. This unique structure makes it a valuable intermediate for synthesizing more complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily sought after by research and development chemists, process development scientists, and manufacturers in fine chemical production. The compound's reactivity profile allows for its use in constructing heterocyclic systems and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing specific receptor-binding activities.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, or fungicides where its aromatic amine moiety is incorporated into the active ingredient.
• Dye and Pigment Precursor: Serves as a starting material for the development of azo dyes and other complex colorants due to the presence of the diazotizable aromatic amine group.
• Polymer Chemistry: Can be utilized as a monomer or chain modifier in the production of specialty polymers, such as polyamides or polyimides, to introduce specific functional properties.
• Chemical Research (R&D): Employed in academic and industrial laboratories for methodological studies in organic synthesis, including amide coupling and aromatic substitution reactions.
• Ligand Synthesis for Catalysis: Acts as a precursor for creating chelating ligands used in metal-catalyzed reactions, leveraging the nitrogen donor atoms.

Basic Information

Product Name	n-(2-Aminophenyl)-2-Methylbutanamide (Saltdata: Free)
CAS No.	946768-61-2
Molecular Formula	C11H16N2O
Molecular Weight	192.26 g/mol
Synonyms	2-Amino-N-(2-aminophenyl)-2-methylbutanamide; 2-Methyl-2-[(2-aminophenyl)amino]butanamide; 2-Amino-2-methyl-N-(2-aminophenyl)butyramide; Butanamide, N-(2-aminophenyl)-2-amino-2-methyl-; (2-Aminophenyl)(1-amino-1-methylpropyl)ketone amine; 2-Methyl-2-(2-aminophenylamino)butyramide; Free base of 946768-61-2
EINECS	Contact for details

Quality Control

Our n-(2-Aminophenyl)-2-Methylbutanamide is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) that include results from HPLC, NMR, and other relevant spectroscopic and chromatographic methods. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply and traceability for critical R&D and production applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized (store under inert atmosphere) and is light-sensitive (store away from light). For long-term storage, consider packaging under an inert gas such as nitrogen or argon. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.