Description

Fmoc-4-(Aminomethyl)-Oxan-4-Carboxylic Acid is a high-purity, protected amino acid derivative designed for advanced solid-phase peptide synthesis (SPPS). This compound matters as a critical building block for introducing the unique 4-(aminomethyl)-oxan-4-carboxylic acid moiety into peptide chains, enabling the creation of novel peptide structures with potential for enhanced stability and bioactivity. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of therapeutic peptides, peptidomimetics, and chemical biology probes.

Application

• Solid-Phase Peptide Synthesis (SPPS): As a key Fmoc-protected amino acid for the automated synthesis of complex peptides.
• Pharmaceutical Research & Development: For constructing novel peptide-based drug candidates and investigating structure-activity relationships (SAR).
• Peptidomimetic Design: Incorporation into non-natural peptide backbones to improve metabolic stability and binding affinity.
• Chemical Biology: Used as a specialized building block in the synthesis of peptide libraries for screening and probe development.
• Bioconjugation: The carboxylic acid and protected amine functionalities allow for selective modification and linker attachment.

Basic Information

Product Name	Fmoc-4-(Aminomethyl)-Oxan-4-Carboxylic Acid
CAS No.	946716-29-6
Molecular Formula	C₂₂H₂₃NO₅
Molecular Weight	381.42 g/mol
Synonyms	Fmoc-Amod-Oca-OH; 4-({[(9H-Fluoren-9-yl)methoxy]carbonyl}aminomethyl)oxane-4-carboxylic acid; Fmoc-AMOD-OH; N-α-Fmoc-4-(aminomethyl)tetrahydro-2H-pyran-4-carboxylic acid; Fmoc-protected 4-(aminomethyl)tetrahydropyran-4-carboxylic acid; N-Fmoc-4-(aminomethyl)oxane-4-carboxylic acid; Fmoc-4-(aminomethyl)tetrahydropyran-4-carboxylic acid; Fmoc-AMOD
EINECS	Contact for details

Quality Control

Our Fmoc-4-(Aminomethyl)-Oxan-4-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided to guarantee consistency and support your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.