Description

4-Fluoro-2-(Methoxymethyl)Phenylboronic Acid is a specialized organoboron compound serving as a critical building block in modern synthetic chemistry. Its value lies in its role as a versatile coupling reagent in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), especially those containing fluorinated biphenyl or heterobiaryl motifs.
• Agrochemical Synthesis: Used in creating advanced herbicides, fungicides, and insecticides that require specific fluorinated aromatic frameworks for enhanced activity and selectivity.
• Material Science Research: Serves as a monomer or building block for developing organic electronic materials, such as those used in OLEDs and organic photovoltaics.
• Ligand and Catalyst Development: Employed in the preparation of sophisticated ligands for transition metal catalysis and organocatalysts.
• Chemical Biology Probes: Utilized in the synthesis of fluorinated molecular probes and tags for imaging and diagnostic applications.
• Custom Synthesis & Contract Manufacturing: A vital reagent for custom synthesis houses and CROs/CMOs serving the life sciences sector.

Basic Information

Product Name	4-Fluoro-2-(Methoxymethyl)Phenylboronic Acid
CAS No.	946607-86-9
Molecular Formula	C9H12BFO3
Molecular Weight	197.99 g/mol
Synonyms	(4-Fluoro-2-(methoxymethyl)phenyl)boronic acid; 2-(Methoxymethyl)-4-fluorobenzeneboronic acid; 4-Fluoro-2-methoxymethylbenzeneboronic acid; B-[4-Fluoro-2-(methoxymethyl)phenyl]boronic acid; 946607-86-9; 4-Fluoro-2-methoxymethylphenylboronic acid
EINECS	Contact for details

Quality Control

Every batch of 4-Fluoro-2-(Methoxymethyl)Phenylboronic Acid is manufactured under strict quality management systems and undergoes comprehensive analytical testing. We ensure compliance with stringent internal specifications, which typically include identity confirmation by NMR and FT-IR, purity assessment by HPLC, and control of key impurities. A Certificate of Analysis (COA) detailing batch-specific results is provided with each shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.