Description

1,3-Difluoro-2-Ethoxybenzene, 2,6-Difluorophenyl Ethyl Ether is a high-purity fluorinated aromatic ether building block of significant commercial importance. This compound is valued for its role as a versatile intermediate in advanced organic synthesis, enabling the introduction of fluorine and alkoxy functionalities into complex molecular architectures. It is primarily sought after by R&D and production teams in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a difluorophenoxy moiety.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where the fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal Materials: Serves as a building block for fluorinated components in liquid crystal displays (LCDs) due to its influence on dielectric anisotropy and viscosity.
• Organic Electronics: Employed in the research and development of organic semiconductors and electro-optical materials.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed reactions like Suzuki-Miyaura or Buchwald-Hartwig amination for constructing complex biaryl systems.
• Chemical Research & Development: A valuable reagent for medicinal chemistry and material science research exploring structure-activity relationships.

Basic Information

Product Name	1,3-Difluoro-2-Ethoxybenzene, 2,6-Difluorophenyl Ethyl Ether
CAS No.	946078-87-1
Molecular Formula	C8H8F2O
Molecular Weight	158.15 g/mol
Synonyms	2,6-Difluorophenyl ethyl ether; 1-Ethoxy-2,6-difluorobenzene; 2-Ethoxy-1,3-difluorobenzene; Benzene, 1,3-difluoro-2-ethoxy-; 2,6-Difluoroanisole, O-ethyl derivative; Ethyl 2,6-difluorophenyl ether; 1,3-Difluoro-2-ethoxybenzene
EINECS	Contact for details

Quality Control

Our 1,3-Difluoro-2-Ethoxybenzene is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical specifications are provided and available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and oxidizing agents. Recommended storage temperature is 2-8°C for long-term stability, although the product is stable at room temperature for shorter periods.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.