Description

4-(Bromomethyl)-2-Pyrrolidinone is a versatile brominated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key electrophilic intermediate, enabling the introduction of functionalized pyrrolidinone moieties into complex molecular architectures. Pharmaceutical, agrochemical, and material science researchers need it for the development of novel active ingredients and functional polymers, leveraging its reactive bromomethyl group for further derivatization.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly those targeting neurological disorders and as protease inhibitors.
• Agrochemical Synthesis: Used in the research and development of new herbicides and fungicides, where the pyrrolidinone core contributes to biological activity.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Polymer Modification: Acts as a functional monomer or cross-linking agent to impart specific properties to specialty polymers and resins.
• Chemical Biology Probes: Utilized in the design and synthesis of activity-based probes and molecular tags for studying enzyme function.
• Custom Synthesis and R&D: A valuable reagent for contract research organizations and academic laboratories exploring new synthetic methodologies.

Basic Information

Product Name	4-(Bromomethyl)-2-Pyrrolidinone
CAS No.	945671-51-2
Molecular Formula	C5H8BrNO
Molecular Weight	178.03 g/mol
Synonyms	4-(Bromomethyl)pyrrolidin-2-one; 2-Pyrrolidinone, 4-(bromomethyl)-; 4-Bromomethyl-2-pyrrolidinone; 4-(Bromomethyl)-2-oxopyrrolidine; 4-Bromomethyl-2-oxopyrrolidine; N/A
EINECS	Contact for details

Quality Control

Our 4-(Bromomethyl)-2-Pyrrolidinone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and process development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is available for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.