Description

tert-Butyl 2-Hydroxycyclopentylcarbamate is a specialized carbamate derivative that serves as a crucial chiral building block and synthetic intermediate in advanced organic synthesis. This compound is valued for its unique structural features, which enable the controlled introduction of functionalized cyclopentyl motifs into complex molecular architectures. It is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in protease inhibitor and cardiovascular drug research.
• Agrochemical Synthesis: Building block for creating advanced pesticides and herbicides with specific stereochemical configurations.
• Organic Synthesis Reagent: Used in asymmetric synthesis, ring-opening reactions, and as a protected amino alcohol precursor.
• Peptidomimetics Research: Employed in the design and synthesis of peptide analogs and conformationally restricted scaffolds for drug discovery.
• Material Science: Potential monomer or modifier in the synthesis of specialized polymers and functional materials.
• Academic & Contract Research: Serves as a valuable reagent for methodological development and exploratory chemistry in university and CRO laboratories.

Basic Information

Product Name	tert-Butyl 2-Hydroxycyclopentylcarbamate
CAS No.	945652-35-7
Molecular Formula	C10H19NO3
Molecular Weight	201.26 g/mol
Synonyms	N-(tert-Butoxycarbonyl)-2-hydroxycyclopentylamine; 2-Hydroxycyclopentylcarbamic Acid tert-Butyl Ester; tert-Butyl N-(2-Hydroxycyclopentyl)carbamate; BOC-2-Hydroxycyclopentylamine; (1R,2S)-rel-2-[[(tert-Butoxy)carbonyl]amino]cyclopentanol; (1S,2R)-rel-2-[[(tert-Butoxy)carbonyl]amino]cyclopentanol; 2-Aminocyclopentanol tert-Butylcarbamate Derivative
EINECS	Contact for details

Quality Control

Our tert-Butyl 2-Hydroxycyclopentylcarbamate is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity determination, to ensure it meets the high standards required for research and process development. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee (or as specified)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.