Description

Benzeneacetic Acid, 4-Amino-3-Fluoro-, Ethyl Ester is a high-purity fluorinated aromatic building block of significant importance in advanced organic synthesis. This compound is valued for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, where the fluorine atom and amino group enable precise modulation of biological activity and physicochemical properties. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly in oncology, central nervous system (CNS), and anti-infective therapeutic areas.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging the fluorine substituent for enhanced efficacy and environmental profile.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Fluorinated Fine Chemicals: Employed in the production of specialty fluorinated compounds for materials science and electronic chemicals.
• Peptidomimetics & Bio-conjugates: The ethyl ester and amino functional groups make it suitable for constructing peptide analogs and bioconjugation linkers.

Basic Information

Product Name	Benzeneacetic Acid, 4-Amino-3-Fluoro-, Ethyl Ester
CAS No.	945561-62-6
Molecular Formula	C10H12FNO2
Molecular Weight	197.21 g/mol
Synonyms	Ethyl 4-Amino-3-fluorobenzeneacetate; 4-Amino-3-fluorophenylacetic Acid Ethyl Ester; 2-(4-Amino-3-fluorophenyl)acetic Acid Ethyl Ester; 3-Fluoro-4-aminophenylacetic Acid Ethyl Ester; Ethyl (4-Amino-3-fluorophenyl)acetate; 945561-62-6; 4-Amino-3-fluoro-benzeneacetic acid ethyl ester
EINECS	Contact for details

Quality Control

Our Benzeneacetic Acid, 4-Amino-3-Fluoro-, Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Related Substances (HPLC)	Total impurities ≤2.0%
Single Unknown Impurity	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.