Description

1-Bromo-4-Prop-2-Yn-1-Ylbenzene is a high-purity aromatic alkyne building block, essential for advanced organic synthesis and materials science research. Its unique structure, featuring both a bromo substituent and a terminal alkyne group, makes it a versatile intermediate for cross-coupling reactions and click chemistry. This compound is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty polymer industries to construct complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for the construction of active pharmaceutical ingredients (APIs) via Sonogashira, Suzuki, and other palladium-catalyzed cross-coupling reactions.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators that require aryl-alkyne motifs.
• Material Science & Polymer Chemistry: Serves as a monomer or functionalizing agent for creating conjugated polymers, dendrimers, and other advanced materials with tailored electronic or optical properties.
• Click Chemistry Reagent: The terminal alkyne group is ideal for Huisgen 1,3-dipolar cycloaddition (copper-catalyzed azide-alkyne cycloaddition) to create triazole linkages in bioconjugation and polymer grafting.
• Ligand & Catalyst Development: Employed as a precursor for synthesizing specialized phosphine or N-heterocyclic carbene (NHC) ligands used in homogeneous catalysis.
• Chemical Biology Probes: Useful for labeling biomolecules or creating chemical probes for studying biological processes.

Basic Information

Product Name	1-Bromo-4-Prop-2-Yn-1-Ylbenzene
CAS No.	944903-27-9
Molecular Formula	C9H7Br
Molecular Weight	195.06 g/mol
Synonyms	4-Bromophenylacetylene; 1-Bromo-4-ethynylbenzene; p-Bromophenylacetylene; (4-Bromophenyl)ethyne; 4-Ethynyl-1-bromobenzene; 4-Bromoethynylbenzene; p-Ethynylbromobenzene; 4-Bromobenzeneacetylene
EINECS	Contact for details

Quality Control

Our 1-Bromo-4-Prop-2-Yn-1-Ylbenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specified parameters. Our quality commitment ensures material consistency and reliability for your critical research and development processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flames. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.