Description

3-Bromo-1-Phenylpropyne is a versatile halogenated alkyne building block of significant importance in advanced organic synthesis. Its reactive bromine and terminal alkyne functionalities make it a key intermediate for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries, enabling the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of compounds with acetylene-linked pharmacophores.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators that require a phenylacetylene core structure.
• Material Science & Polymer Chemistry: Serves as a monomer or cross-linking agent for creating specialty polymers, conductive materials, and liquid crystals.
• Organic Synthesis Reagent: Employed in Sonogashira coupling, click chemistry, and other palladium-catalyzed cross-coupling reactions to introduce phenylacetylene units.
• Ligand & Catalyst Development: Used to synthesize novel phosphine or nitrogen-based ligands for homogeneous catalysis.
• Chemical Research: A valuable reagent in academic and industrial R&D for exploring new synthetic methodologies and creating molecular libraries.

Basic Information

Product Name	3-Bromo-1-Phenylpropyne
CAS No.	1794-48-5
Molecular Formula	C9H7Br
Molecular Weight	195.06 g/mol
Synonyms	1-Phenyl-3-bromopropyne; 3-Bromophenylacetylene; (3-Bromoprop-1-yn-1-yl)benzene; 3-Bromo-1-phenyl-1-propyne; Benzene, (3-bromo-1-propyn-1-yl)-; Bromo(phenylethynyl)methane
EINECS	217-273-9

Quality Control

We maintain stringent quality control protocols for 3-Bromo-1-Phenylpropyne to ensure batch-to-batch consistency and reliability for your critical syntheses. Our standard grade typically meets a purity specification of ≥97% (by GC or HPLC), with rigorous testing for identity, purity, and key impurities. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment. Custom synthesis and higher purity grades (≥98%, ≥99%) are available upon request to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.