Description

1-Phenyl-1-Hexyne is a versatile terminal alkyne building block characterized by its phenyl-substituted structure. This compound is of significant value in organic synthesis, particularly in metal-catalyzed cross-coupling reactions and cycloadditions, enabling the construction of complex molecular architectures. It serves as a critical intermediate for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, where precise carbon-carbon bond formation is essential.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs) and novel drug candidates via Sonogashira, Glaser, and other coupling reactions.
• Agrochemical Synthesis: Used in the production of specialized pesticides, herbicides, and plant growth regulators that require aryl-alkyne motifs.
• Material Science Research: Serves as a monomer or precursor in the development of conjugated polymers, organic semiconductors, and liquid crystals.
• Organic Synthesis Reagent: Employed in academic and industrial R&D for constructing complex natural products, dyes, and ligands for catalysis.
• Chemical Biology Probes: Utilized in click chemistry applications for bioconjugation and labeling of biomolecules due to its terminal alkyne functionality.

Basic Information

Product Name	1-Phenyl-1-Hexyne
CAS No.	1129-65-3
Molecular Formula	C₁₂H₁₄
Molecular Weight	158.24 g/mol
Synonyms	Hex-1-yn-1-ylbenzene; Phenylhex-1-yne; 1-Hexynylbenzene; Benzene, (1-hexynyl)-; n-Hex-1-ynylbenzene; 1-Phenylhex-1-yne; (Hex-1-yn-1-yl)benzene
EINECS	214-447-9

Quality Control

Our 1-Phenyl-1-Hexyne is produced under stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including chromatographic purity analysis and identity confirmation, to ensure it meets the high standards required for advanced synthetic applications. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated place away from heat and ignition sources. Due to its highly volatile nature, the container must be kept tightly sealed when not in use to prevent evaporation and concentration changes. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.