Description

5-Phenyl-1-Pentyne is a versatile terminal alkyne building block with a phenyl substituent, widely used in organic synthesis and materials science. Its value lies in its ability to participate in diverse coupling and cycloaddition reactions, enabling the efficient construction of complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity intermediates for their development and production processes.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of bioactive molecules, including potential drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and plant growth regulators.
• Material Science Research: Serves as a monomer or precursor for the development of novel polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: An effective substrate in Sonogashira, Glaser, and other palladium-catalyzed coupling reactions to form carbon-carbon bonds.
• Click Chemistry: Utilized in Huisgen 1,3-dipolar cycloaddition (azide-alkyne click chemistry) for bioconjugation and polymer functionalization.
• Organic Synthesis Reagent: Employed in academic and industrial R&D laboratories for the synthesis of complex natural products and fine chemicals.

Basic Information

Product Name	5-Phenyl-1-Pentyne
CAS No.	1823-14-9
Molecular Formula	C11H12
Molecular Weight	144.21 g/mol
Synonyms	1-Pentyne, 5-phenyl-; 5-Phenylpentyne; 5-Phenylpent-1-yne; Phenylpent-1-yne; (Phenylbutyl)acetylene; 1-Phenyl-4-pentyne; 4-Phenyl-1-butyne (common misnomer, verify structure); Pent-1-yn-5-ylbenzene
EINECS	Contact for details

Quality Control

Our 5-Phenyl-1-Pentyne is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure high chemical purity and identity confirmation. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting the exact specifications and results. We adhere to cGMP principles where applicable to support our clients in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated place at a controlled room temperature (15-25°C). Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use and stored away from heat, sparks, and open flame. Keep under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.