Description

3-Pentyn-1-ol is a terminal alkyne alcohol with the molecular formula C5H8O, serving as a versatile building block in organic synthesis. Its value lies in its bifunctional nature, featuring both a reactive hydroxyl group and a terminal alkyne moiety, enabling diverse chemical transformations. This compound is primarily needed by R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries for applications such as click chemistry, Sonogashira couplings, and the synthesis of complex molecular architectures.

Application

• Pharmaceutical Intermediates: A key synthon for constructing active pharmaceutical ingredients (APIs) and novel drug candidates via coupling reactions.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and plant growth regulators.
• Material Science: Serves as a monomer or cross-linking agent in the development of specialty polymers and advanced materials.
• Click Chemistry: An ideal substrate for copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions to create triazole linkages.
• Organic Synthesis: Employed in Sonogashira, Heck, and other palladium-catalyzed cross-coupling reactions to form carbon-carbon bonds.
• Ligand and Catalyst Development: Useful for synthesizing novel chelating ligands and organometallic catalysts.
• Flavor and Fragrance Industry: Potential intermediate for synthesizing specific aroma compounds.
• Academic and Industrial R&D: A valuable reagent for exploratory chemistry and process optimization in laboratory settings.

Basic Information

Product Name	3-Pentyn-1-ol
CAS No.	10229-10-4
Molecular Formula	C5H8O
Molecular Weight	84.12 g/mol
Synonyms	3-Pentyn-1-ol; Pent-3-yn-1-ol; 1-Hydroxy-3-pentyne; 3-Pentyne-1-ol; Ethyl propargyl carbinol; 3-Butyn-1-ol, 2-methyl-; HC≡CCH2CH2CH2OH
EINECS	233-571-6

Quality Control

Our 3-Pentyn-1-ol is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We adhere to cGMP principles where applicable to support our customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat, sparks, and open flame. Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use to prevent evaporation and concentration of peroxides. Recommended storage temperature is 2-8°C for long-term stability. Keep away from strong oxidizing agents and acids.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.