Description

4-Chloro-2-Methyl-7,8-Dihydroquinazolin-6(5H)-One is a high-purity, synthetically versatile heterocyclic building block of significant interest in advanced organic synthesis. This compound serves as a critical intermediate for the development of novel pharmaceutical candidates, particularly in medicinal chemistry research targeting specific enzyme inhibition. It is primarily needed by R&D laboratories, fine chemical manufacturers, and pharmaceutical companies engaged in the synthesis of complex molecules for drug discovery and development programs.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel quinazoline-based drug candidates for oncology and other therapeutic areas.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery.
• Chemical Biology Probe Development: Serves as a starting material for creating tool compounds to study biological pathways and target validation.
• Fine Chemical Synthesis: Employed in multi-step synthetic routes to produce complex, high-value specialty chemicals.
• Agrochemical Research: Potential intermediate in the development of new active ingredients for crop protection.

Basic Information

Product Name	4-Chloro-2-Methyl-7,8-Dihydroquinazolin-6(5H)-One
CAS No.	944902-33-4
Molecular Formula	C10H9ClN2O
Molecular Weight	208.64 g/mol
Synonyms	4-Chloro-2-methyl-5,6,7,8-tetrahydroquinazolin-6-one; 6(5H)-Quinazolinone, 4-chloro-7,8-dihydro-2-methyl-; 4-Chloro-2-methyl-7,8-dihydroquinazolin-6(5H)-one; 4-Chloro-2-methyl-5,6,7,8-tetrahydroquinazolin-6-ol; 944902-33-4; 4-Chloro-2-methyl-5,6,7,8-tetrahydro-6-quinazolinone
EINECS	Contact for details

Quality Control

Our 4-Chloro-2-Methyl-7,8-Dihydroquinazolin-6(5H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.