Description

tert-Butyl[(5-Oxopyrrolidin-2-Yl)Methyl]Carbamate is a high-purity, advanced pharmaceutical intermediate featuring a protected amine group on a pyrrolidinone scaffold. This compound is critical for the synthesis of complex molecules, offering a versatile handle for further chemical elaboration in drug discovery and development. It is primarily utilized by research institutions and pharmaceutical companies engaged in the creation of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and metabolic disorder targets.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly those targeting neurological and psychiatric conditions.
• Protease Inhibitor Research: Serves as a core structural component in the development of novel protease inhibitors for therapeutic applications.
• Peptidomimetic Chemistry: Used to construct peptidomimetic scaffolds that mimic natural peptides for enhanced stability and bioavailability in drug design.
• Medicinal Chemistry & SAR Studies: Enables structure-activity relationship (SAR) exploration by providing a modifiable point on the pyrrolidinone ring system.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the cGMP production of clinical trial materials.
• Academic Research: Employed in university and institutional labs for methodological development in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	tert-Butyl[(5-Oxopyrrolidin-2-Yl)Methyl]Carbamate
CAS No.	944728-08-9
Molecular Formula	C10H18N2O3
Molecular Weight	214.26 g/mol
Synonyms	2-[[(tert-Butoxycarbonyl)amino]methyl]-5-pyrrolidinone; 1-Boc-2-(aminomethyl)-5-pyrrolidinone; tert-Butyl N-[(5-oxopyrrolidin-2-yl)methyl]carbamate; 2-(Boc-aminomethyl)-2-pyrrolidin-5-one; (5-Oxo-2-pyrrolidinylmethyl)carbamic acid tert-butyl ester; Boc-2-pyrrolidinonemethylamine; N-Boc-2-aminomethyl-5-pyrrolidinone
EINECS	Contact for details

Quality Control

Our tert-Butyl[(5-Oxopyrrolidin-2-Yl)Methyl]Carbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP guidelines where required, ensuring suitability for advanced research and pre-clinical development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.