Description

Acetic Acid, 2-[2-[2-(2-Propyn-1-Yloxy)Ethoxy]Ethoxy]- is a specialized functionalized acetic acid derivative featuring a terminal alkyne group linked via a triethylene glycol spacer. This unique molecular architecture makes it a versatile chemical building block for advanced synthesis, particularly in click chemistry and polymer science. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials sectors who require high-purity, reactive intermediates for creating novel compounds with tailored properties.

Application

• Click Chemistry Reagent: The terminal alkyne group enables efficient Huisgen 1,3-dipolar cycloaddition (copper-catalyzed azide-alkyne cycloaddition, CuAAC) for bioconjugation and polymer functionalization.
• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs) and prodrugs, where its hydrophilic linker can improve solubility.
• Polymer Modification & Crosslinking: Serves as a functional monomer or crosslinking agent for creating hydrogels, smart materials, and surface coatings with specific responsive properties.
• Bioconjugation & Probe Synthesis: A key precursor for attaching fluorescent dyes, affinity tags (e.g., biotin), or other reporter molecules to biomolecules like proteins, peptides, and oligonucleotides.
• Agrochemical Synthesis: Employed in the development of novel herbicides, fungicides, and plant growth regulators that require specific molecular tethering.
• Material Science Research: Used to create self-assembled monolayers (SAMs) and modify surfaces for sensor development and nanotechnology applications.

Basic Information

Product Name	Acetic Acid, 2-[2-[2-(2-Propyn-1-Yloxy)Ethoxy]Ethoxy]-
CAS No.	944561-46-0
Molecular Formula	C11H18O6
Molecular Weight	246.26 g/mol
Synonyms	2-[2-[2-(2-Propyn-1-yloxy)ethoxy]ethoxy]acetic Acid; Propargyl-PEG3-acetic Acid; Alkyne-PEG3-Acid; 2,5,8,11-Tetraoxatetradec-13-yn-14-oic Acid; 3,6,9-Trioxa-12-dodecynoic Acid; Propargyl-O-(CH2CH2O)3-CH2COOH; Terminal Alkyne PEG Acid; Acetic acid, 2,2'-[2,2'-(2-propyn-1-yloxy)diethoxy]diethoxy]-
EINECS	Contact for details

Quality Control

Our production of Acetic Acid, 2-[2-[2-(2-Propyn-1-Yloxy)Ethoxy]Ethoxy]- adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for sensitive applications like pharmaceutical R&D. Each lot is characterized by advanced analytical techniques including NMR, HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). This compound is easily oxidized; for long-term storage, consider maintaining under an inert atmosphere (e.g., nitrogen or argon) to preserve stability and prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.