Description

Hex-4-Yn-1-Ol CAS NO 928-93-8 is a versatile terminal alkyne alcohol, serving as a crucial bifunctional building block in advanced organic synthesis. Its unique structure, featuring both a hydroxyl group and a terminal alkyne, enables efficient construction of complex molecular architectures through reactions like Sonogashira coupling and click chemistry. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries developing novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Key synthon for constructing active pharmaceutical ingredients (APIs) and drug candidates via coupling reactions.
• Agrochemical Synthesis: Building block for novel herbicides, fungicides, and plant growth regulators.
• Material Science: Monomer for synthesizing specialty polymers, dendrimers, and functionalized surfaces with tailored properties.
• Click Chemistry: Ideal substrate for copper-catalyzed azide-alkyne cycloaddition (CuAAC) to create triazole linkages in bioconjugation and polymer chemistry.
• Ligand & Catalyst Development: Precursor for synthesizing novel phosphine and N-heterocyclic carbene (NHC) ligands used in homogeneous catalysis.
• Organic Synthesis: Versatile reagent for carbon-carbon bond formation, including Sonogashira, Glaser, and Cadiot-Chodkiewicz couplings.
• Life Sciences Research: Used in probe and biomarker development for biochemical assays and imaging applications.

Basic Information

Product Name	Hex-4-Yn-1-Ol
CAS No.	928-93-8
Molecular Formula	C₆H₁₀O
Molecular Weight	98.14 g/mol
Synonyms	4-Hexyn-1-ol; 1-Hydroxy-4-hexyne; 4-Hexyne-1-ol; But-2-ynylmethanol; 3-Butyn-1-ylcarbinol; 4-Hexynol; HC≡CCH₂CH₂CH₂OH
EINECS	213-187-9

Quality Control

Our Hex-4-Yn-1-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, open flames, and oxidizing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.