Description

Bis(4-Bromophenyl)Acetylene is a high-purity organic building block featuring a rigid, linear acetylene core symmetrically substituted with bromophenyl groups. This compound is valued for its role as a key intermediate in advanced material synthesis and pharmaceutical research, enabling the construction of complex molecular architectures. It is essential for R&D chemists and process engineers in the pharmaceutical, agrochemical, and organic electronics industries who require reliable, high-quality precursors for cross-coupling reactions and polymer development.

Application

• Pharmaceutical Intermediate: Serves as a critical synthon in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates via Sonogashira and other palladium-catalyzed cross-coupling reactions.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides, leveraging its bromine substituents for further functionalization.
• Material Science & Organic Electronics: Acts as a fundamental monomer or linker in the creation of conjugated polymers, organic semiconductors, and liquid crystals for OLEDs and photovoltaic devices.
• Ligand & Catalyst Preparation: Employed in the synthesis of specialized phosphine or N-heterocyclic carbene (NHC) ligands for asymmetric catalysis.
• Academic & Industrial R&D: A versatile reagent for exploring new organic reactions and constructing complex polycyclic aromatic hydrocarbons (PAHs) or molecular wires.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for bio-conjugation and imaging applications.

Basic Information

Product Name	Bis(4-Bromophenyl)Acetylene
CAS No.	2789-89-1
Molecular Formula	C14H8Br2
Molecular Weight	336.02 g/mol
Synonyms	1,2-Bis(4-bromophenyl)ethyne; 4,4'-Dibromodiphenylacetylene; p,p'-Dibromodiphenylacetylene; 1-Bromo-4-[(4-bromophenyl)ethynyl]benzene; NSC 404087; Bis(p-bromophenyl)acetylene
EINECS	220-514-5

Quality Control

Our Bis(4-Bromophenyl)Acetylene is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and melting point determination, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with full traceability are provided and available upon request, supporting compliance in cGMP and ISO 9001 environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	185 - 190 °C
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.