Description

Rafivirumab CAS NO 944548-37-2 is a high-purity monoclonal antibody (mAb) designed for advanced therapeutic applications. This product is critical for research and development in targeted biological therapies, offering precise action against specific antigens. It is primarily utilized by pharmaceutical developers, biotech research institutions, and contract manufacturing organizations (CMOs) engaged in oncology and immunology drug discovery.

Application

• Oncology Research & Therapeutics: Primary application in the development of targeted cancer treatments and immunotherapies.
• Biopharmaceutical Development: Used as a key intermediate or reference standard in the formulation of monoclonal antibody-based drugs.
• Preclinical & Clinical Studies: Serves as a critical reagent for in vitro and in vivo studies to evaluate efficacy and mechanism of action.
• Diagnostic Assay Development: Employed in the creation of sensitive immunoassays and diagnostic kits for disease detection.
• Process Development & Scale-up: Essential for optimizing fermentation, purification, and characterization processes in biomanufacturing.

Basic Information

Product Name	Rafivirumab
CAS No.	944548-37-2
Molecular Formula	Contact for details
Molecular Weight	Approx. 145-150 kDa (Contact for details)
Synonyms	Anti-Rafivirumab mAb; Rafivirumab Monoclonal Antibody; Immunoglobulin G1, anti-(human target); Therapeutic Monoclonal Antibody; mAb Rafivirumab; RAFI-mAb; Biologic RAF-001
EINECS	Contact for details

Quality Control

Our Rafivirumab is manufactured under stringent quality systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, potency, and safety, aligning with ICH Q6B guidelines for biotechnological products. A comprehensive Certificate of Analysis (COA) detailing purity (by SEC-HPLC and CE-SDS), endotoxin levels, sterility, and binding activity is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C to -80°C. Avoid repeated freeze-thaw cycles. The product is hygroscopic (moisture-sensitive); ensure containers are sealed under controlled humidity conditions upon opening.

Specification

Item	Specification
Appearance	Clear to slightly opalescent, colorless to pale yellow liquid
Identification (SEC-HPLC / MS)	Conforms to reference standard
Purity (SEC-HPLC)	≥ 95.0% (Monomer)
Purity (CE-SDS, reduced)	≥ 90.0% (Heavy & Light Chain)
Protein Concentration	As per COA (typically 1-10 mg/mL)
Endotoxin	< 1.0 EU/mg
Sterility	Sterile (or as specified)
Binding Activity (ELISA/SPR)	≥ 90% relative activity

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.