Description

Dermorphin CAS NO 77614-16-5 is a potent synthetic heptapeptide with significant opioid receptor agonist activity. Its primary value lies in its high selectivity and affinity for μ-opioid receptors, making it a critical tool for advanced pharmacological research and development. This compound is essential for researchers and developers in the pharmaceutical and biotechnology sectors, particularly those focused on neurobiology, pain management, and the study of opioid receptor mechanisms.

Application

• Neuroscience Research: Used as a selective μ-opioid receptor agonist to study receptor binding, signal transduction, and neural pathways in the central nervous system.
• Analgesic Mechanism Studies: Serves as a reference standard in preclinical research to investigate the mechanisms of pain relief and to develop novel analgesic compounds.
• Biochemical Assay Development: Employed in the development and validation of high-throughput screening (HTS) assays and competitive binding assays for drug discovery.
• Reference Standard: Used as a high-purity analytical standard in quality control laboratories for peptide identification and quantification via HPLC and mass spectrometry.
• Academic & Institutional Research: A key reagent for universities and research institutes conducting fundamental studies in pharmacology, physiology, and medicinal chemistry.

Basic Information

Product Name	Dermorphin
CAS No.	77614-16-5
Molecular Formula	C₄₀H₅₀N₁₀O₁₀
Molecular Weight	802.9 g/mol
Synonyms	Dermorphin; H-Tyr-D-Ala-Phe-Gly-Tyr-Pro-Ser-NH₂; Dermorphin acetate; D-Ala2-Dermorphin; Dermorphin (1-7); Tyr-D-Ala-Phe-Gly-Tyr-Pro-Ser-NH2; Mu-opioid receptor agonist peptide; [D-Ala2]-Dermorphin
EINECS	Contact for details

Quality Control

Our Dermorphin is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry for identity confirmation, and amino acid analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. The product is hygroscopic (moisture-sensitive) and light-sensitive. For long-term storage, keep desiccated. Allow the vial to reach room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 2.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%
Solubility	Soluble in water, acetic acid

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.