Description

Neuropeptide S (1-10) (Human) is a synthetic bioactive peptide fragment corresponding to the N-terminal decapeptide of the full-length human Neuropeptide S. This compound is a critical research tool for investigating the Neuropeptide S (NPS) receptor system, which is involved in modulating arousal, anxiety, and stress responses. It is primarily utilized by pharmaceutical R&D teams, academic neuroscientists, and biochemical researchers focused on central nervous system (CNS) drug discovery and neuropharmacology.

Application

• Neuroscience Research: Used as a reference standard and agonist in studies of the NPS/NPSR system to understand its role in anxiety, wakefulness, and stress-related behaviors.
• Drug Discovery & Screening: Serves as a key pharmacological tool for high-throughput screening (HTS) assays to identify novel NPS receptor modulators, agonists, or antagonists.
• Biochemical Assay Development: Employed in the development and validation of receptor binding assays, calcium flux assays, and other functional cellular assays.
• In Vitro & Ex Vivo Studies: Applied in cell culture models and tissue preparations to study receptor signaling pathways and downstream effects.
• Peptide Structure-Activity Relationship (SAR) Studies: Acts as a core structure for synthesizing and testing analog peptides to map critical residues for receptor interaction and stability.
• Academic & Clinical Research: Supports fundamental research into the physiological and pathological roles of Neuropeptide S in the brain.

Basic Information

Product Name	Neuropeptide S (1-10) (Human)
CAS No.	904910-39-0
Molecular Formula	C52H82N16O14S
Molecular Weight	1171.4 g/mol
Synonyms	NPS (1-10); Human Neuropeptide S (1-10); SFRNGVGSGV; H-Ser-Phe-Arg-Asn-Gly-Val-Gly-Ser-Gly-Val-OH; Neuropeptide S fragment 1-10; NPS(1-10) amide (if amidated); GQ0860 (potential catalog number)
EINECS	Contact for details

Quality Control

Our Neuropeptide S (1-10) (Human) is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity for research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting the purity, peptide content, and other critical specifications.

Storage

Preserve in a tightly closed container, protected from light. Store desiccated at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC)	Retention time corresponds to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Molecular Weight	1171.4 ± 1.0 Da (by MS)
Solubility	Soluble in water, dilute acetic acid

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.