Description

3-(2-Oxo-3-Phenyltetrahydropyrimidin-1(2H)-Yl)Propanoic Acid is a high-purity, advanced pharmaceutical intermediate with a defined heterocyclic structure. This compound is valued for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex molecular architectures. It is primarily sought by research institutions and manufacturers in the global pharmaceutical and biotechnology sectors for drug discovery and development programs.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of target drug molecules, especially those containing the tetrahydropyrimidinone pharmacophore.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new chemical entities with potential biological activity.
• API Synthesis: Employed in the production route for active pharmaceutical ingredients targeting central nervous system (CNS) disorders, inflammation, or other therapeutic areas.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and scale-up services for the pharmaceutical industry.
• Chemical Reference Standard: Can be utilized as an analytical standard for quality control and method development in regulatory filings.

Basic Information

Product Name	3-(2-Oxo-3-Phenyltetrahydropyrimidin-1(2H)-Yl)Propanoic Acid
CAS No.	944463-71-2
Molecular Formula	C₁₃H₁₄N₂O₃
Molecular Weight	246.26 g/mol
Synonyms	1,2,3,4-Tetrahydro-2-oxo-3-phenyl-1-pyrimidinepropanoic Acid; 3-(2-Oxo-3-phenyl-1,2,3,4-tetrahydropyrimidin-1-yl)propanoic Acid; 3-(3-Phenyl-2-oxotetrahydropyrimidin-1(2H)-yl)propanoic Acid; NSC 796085; 944463-71-2; 3-(2-Oxo-3-phenyl-1,2,3,4-tetrahydropyrimidin-1-yl)propionic Acid
EINECS	Contact for details

Quality Control

Our production of 3-(2-Oxo-3-Phenyltetrahydropyrimidin-1(2H)-Yl)Propanoic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and reliability for critical research and manufacturing applications. All material is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles, generated using validated analytical methods such as HPLC, NMR, and MS. We support compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.