Description

(tert-Butoxy)Carbonyl Ser((9H-Fluoren-9-Yl)Methoxy]Carbonyl Glu(Otbu))-Oh is a sophisticated, orthogonally protected dipeptide building block designed for advanced peptide synthesis. This compound is critical for researchers and manufacturers requiring high-purity intermediates to construct complex peptide sequences with precise control. It is primarily utilized in pharmaceutical R&D and production for the development of therapeutic peptides, APIs, and novel bioactive compounds.

Application

• Solid-Phase Peptide Synthesis (SPPS): As a key protected dipeptide fragment for the efficient, sequential assembly of longer peptide chains.
• Pharmaceutical Intermediate: For the research and cGMP manufacturing of active pharmaceutical ingredients (APIs) for therapeutic peptides.
• Peptide Library Construction: Enables the generation of diverse peptide libraries for drug discovery, screening, and structure-activity relationship (SAR) studies.
• Bioconjugation and Labeling: Serves as a precursor for creating labeled or modified peptides for diagnostic and research applications.
• Academic and Industrial Research: A vital reagent in biochemistry and medicinal chemistry laboratories for studying peptide structure and function.

Basic Information

Product Name	(tert-Butoxy)Carbonyl Ser((9H-Fluoren-9-Yl)Methoxy]Carbonyl Glu(Otbu))-Oh
CAS No.	944283-18-5
Molecular Formula	C35H46N2O10
Molecular Weight	654.75 g/mol
Synonyms	Boc-Ser(Fmoc-Glu(OtBu))-OH; Boc-L-Serine, N-[N-[N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-glutamyl]-O-(1,1-dimethylethyl) ester]; Fmoc-Glu(OtBu)-Ser(Boc)-OH (reverse sequence notation); N-α-Boc-O-(N-ε-Fmoc-γ-O-t-butyl-L-glutamyl)-L-serine; Protected Ser-Glu dipeptide; Boc-Ser(Fmoc-Glu(OtBu))-OH; Peptide building block 944283-18-5
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is characterized by advanced analytical techniques to guarantee identity, purity, and consistency. Certificates of Analysis (COA) detailing purity (typically ≥95% by HPLC), chiral purity, and impurity profiles are available upon request. We support development and production needs from research grade to cGMP standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive); desiccants are recommended for long-term storage. Keep container tightly sealed under an inert atmosphere if specified for high-purity grades.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Chiral Purity	≥ 99.0% (L-isomer)
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.