Description

3-Fluoro-4-(3-Morpholinopropoxy)Phenylboronic Acid is a high-value, functionalized boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its molecular architecture, featuring both a boronic acid group and a morpholine-linked alkoxy chain, makes it an essential reagent for constructing complex molecules via cross-coupling reactions. This compound is primarily sought after by research scientists and process chemists in the pharmaceutical and agrochemical industries for the development of new active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in kinase inhibitor and CNS-active compound research.
• Agrochemical Synthesis: Used in the development of advanced herbicides and fungicides, leveraging its fluorine and boronic acid functionalities for bioactivity.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as polymers and small molecules for OLEDs and sensors.
• Chemical Biology Probes: Serves as a building block for creating bioconjugates and activity-based probes to study biological pathways.
• Catalyst Ligand Development: The morpholine moiety can be utilized in the design of novel ligands for transition metal catalysis.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for use in custom synthesis projects and scale-up campaigns for client-specific molecules.

Basic Information

Product Name	3-Fluoro-4-(3-Morpholinopropoxy)Phenylboronic Acid
CAS No.	944279-32-7
Molecular Formula	C₁₃H₁₉BFNO₄
Molecular Weight	283.11 g/mol
Synonyms	[4-(3-Morpholinopropoxy)-3-fluorophenyl]boronic acid; 3-Fluoro-4-(3-morpholin-4-ylpropoxy)benzeneboronic acid; 3-Fluoro-4-(3-morpholinopropoxy)benzeneboronic acid; B-[4-(3-Morpholinopropoxy)-3-fluorophenyl]boronic acid; 4-(3-Morpholinopropoxy)-3-fluorobenzeneboronic acid; 944279-32-7; AKOS005258065
EINECS	Contact for details

Quality Control

Our 3-Fluoro-4-(3-Morpholinopropoxy)Phenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with full traceability are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) due to its hygroscopic and easily oxidized nature. Allow the container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥95.0%
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.