Description

3-Fluoro-4-(3-(Pyrrolidin-1-Yl)Propoxy)Phenylboronic Acid is a sophisticated boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its value lies in its dual functionality, combining a boronic acid group for Suzuki-Miyaura cross-coupling reactions with a fluorinated aromatic system and a pyrrolidine-containing side chain, enabling the construction of complex, pharmaceutically relevant scaffolds. This high-purity intermediate is essential for research and development chemists in the pharmaceutical and agrochemical industries who are developing new active ingredients, particularly for targeted therapies.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially kinase inhibitors and other small molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides with enhanced efficacy and selectivity.
• Material Science: Serves as a monomer or cross-linking agent in the creation of advanced polymers and functional organic materials.
• Chemical Biology & Proteomics: Employed in the design of chemical probes and affinity ligands for studying biological pathways and protein function.
• Ligand Synthesis: The pyrrolidine moiety makes it a valuable starting point for synthesizing chiral ligands used in asymmetric catalysis.
• Diagnostic Agent Development: Utilized in the research phase for creating novel imaging agents and diagnostic tools.

Basic Information

Product Name	3-Fluoro-4-(3-(Pyrrolidin-1-Yl)Propoxy)Phenylboronic Acid
CAS No.	944279-29-2
Molecular Formula	C₁₃H₁₉BFNO₃
Molecular Weight	267.11 g/mol
Synonyms	[3-Fluoro-4-(3-pyrrolidin-1-ylpropoxy)phenyl]boronic acid; 4-(3-(Pyrrolidin-1-yl)propoxy)-3-fluorobenzeneboronic acid; 3-Fluoro-4-[3-(1-pyrrolidinyl)propoxy]benzeneboronic Acid; B-[3-Fluoro-4-[3-(1-pyrrolidinyl)propoxy]phenyl]boronic acid; 944279-29-2; AKOS005258065; FT-0698308; BDBM50389351.
EINECS	Contact for details

Quality Control

Our production of 3-Fluoro-4-(3-(Pyrrolidin-1-Yl)Propoxy)Phenylboronic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical characterization, including HPLC for purity assessment, NMR for structural confirmation, and mass spectrometry. A detailed Certificate of Analysis (COA) documenting identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.