Description

4-(2-(Dimethylamino)Ethoxy)-3-Fluorophenylboronic Acid is a specialized organoboron compound featuring a dimethylaminoethoxy side chain and a fluorine substituent on the phenyl ring. This unique structure makes it a valuable building block in modern synthetic chemistry, particularly for cross-coupling reactions like the Suzuki-Miyaura reaction. It is primarily utilized by researchers and manufacturers in the pharmaceutical and agrochemical industries for the development of novel active ingredients and complex organic molecules.

Application

• Pharmaceutical Intermediate: A key synthon for constructing complex drug candidates, especially those targeting neurological disorders or cancers.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides with specific activity profiles.
• Material Science Research: Serves as a precursor for creating functionalized polymers or organic electronic materials.
• Suzuki-Miyaura Cross-Coupling: Acts as a critical boronic acid partner for forming carbon-carbon bonds between aromatic systems under mild conditions.
• Ligand and Catalyst Development: The dimethylaminoethoxy moiety can be utilized to develop novel ligands for metal catalysis.
• Chemical Biology Probes: Useful for synthesizing labeled compounds or probes for studying biological processes.

Basic Information

Product Name	4-(2-(Dimethylamino)Ethoxy)-3-Fluorophenylboronic Acid
CAS No.	944279-23-6
Molecular Formula	C10H15BFNO3
Molecular Weight	227.05 g/mol
Synonyms	3-Fluoro-4-[2-(dimethylamino)ethoxy]benzeneboronic acid; [3-Fluoro-4-[2-(dimethylamino)ethoxy]phenyl]boronic acid; 4-[2-(Dimethylamino)ethoxy]-3-fluorobenzeneboronic acid; B-[3-Fluoro-4-[2-(dimethylamino)ethoxy]phenyl]boronic acid; 3-Fluoro-4-(2-(dimethylamino)ethoxy)phenylboronic acid; 944279-23-6; (3-Fluoro-4-(2-(dimethylamino)ethoxy)phenyl)boronic acid
EINECS	Contact for details

Quality Control

Our 4-(2-(Dimethylamino)Ethoxy)-3-Fluorophenylboronic Acid is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistent performance. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specification parameters. Our quality systems support development and cGMP manufacturing requirements for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.