Description

(4-Chloro-2-Fluoro-3-Methylphenyl)Boronic Acid is a high-purity boronic acid derivative, a critical building block in modern synthetic chemistry. Its value lies in enabling precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing new active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key synthon for constructing novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Material Science: Serves as a precursor for synthesizing organic electronic materials, such as those used in OLEDs and organic photovoltaics.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D labs for methodology development and library synthesis.
• Ligand and Catalyst Preparation: Employed in the synthesis of specialized ligands for transition metal catalysis.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke fine chemicals.

Basic Information

Product Name	(4-Chloro-2-Fluoro-3-Methylphenyl)Boronic Acid
CAS No.	944128-92-1
Molecular Formula	C7H7BClFO2
Molecular Weight	187.39 g/mol
Synonyms	4-Chloro-2-fluoro-3-methylbenzeneboronic acid; (4-Chloro-2-fluoro-3-methylphenyl)boronic acid; B-(4-Chloro-2-fluoro-3-methylphenyl)boronic acid; 3-Methyl-4-chloro-2-fluorobenzeneboronic acid; 944128-92-1; Boronic acid, B-(4-chloro-2-fluoro-3-methylphenyl)-; 4-Chloro-2-fluoro-m-tolylboronic acid
EINECS	Contact for details

Quality Control

Our (4-Chloro-2-Fluoro-3-Methylphenyl)Boronic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.