Description

3-(2-Fluoro-Phenyl) Pyrrolidine Hcl is a high-purity fluorinated pyrrolidine derivative, a crucial chiral building block in modern organic synthesis. Its value lies in providing a structurally defined, functionalized scaffold essential for constructing complex molecules with targeted biological activity. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and drug discovery.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) targets.
• Medicinal Chemistry: Used extensively in structure-activity relationship (SAR) studies and lead optimization to modulate the pharmacokinetic and pharmacodynamic properties of drug candidates.
• Agrochemical Research: Employed as a building block in the synthesis of advanced herbicides, fungicides, and pesticides, where the fluorine atom enhances bioactivity and stability.
• Ligand & Catalyst Development: Acts as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis to create enantiomerically pure compounds.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and biological pathways.

Basic Information

Product Name	3-(2-Fluoro-Phenyl) Pyrrolidine Hcl
CAS No.	943843-62-7
Molecular Formula	C10H13FN • HCl
Molecular Weight	201.68 g/mol
Synonyms	3-(2-Fluorophenyl)pyrrolidine hydrochloride; 2-Fluoro-3-pyrrolidinylbenzene hydrochloride; 1-(2-Fluorophenyl)-3-pyrrolidinol hydrochloride (tautomeric form); Pyrrolidine, 3-(2-fluorophenyl)-, hydrochloride; (R/S)-3-(2-Fluorophenyl)pyrrolidine HCl; 943843-62-7; FC-1133 (potential research code)
EINECS	Contact for details

Quality Control

Every batch of 3-(2-Fluoro-Phenyl) Pyrrolidine Hcl is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our standard grade meets high-purity research specifications, with comprehensive testing including chiral purity assessment. A Certificate of Analysis (COA) detailing specific results for each parameter is provided with every shipment, ensuring full traceability and compliance with your research or development protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (or as specified)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.