Description

1-Bromo-4-Chloro-2-Fluoro-3-Methoxybenzene is a high-purity, multi-halogenated aromatic building block of significant importance in advanced organic synthesis. Its unique substitution pattern makes it a critical intermediate for constructing complex molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for researchers and manufacturers developing active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials who require reliable access to high-quality, structurally precise intermediates.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially in the development of fluorinated and halogenated active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where the specific halogen pattern confers desired biological activity and stability.
• Material Science Research: Serves as a precursor for the development of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to introduce complex aryl groups into target molecules.
• Life Sciences & Diagnostics: Potential use in the synthesis of molecular probes, tags, and other reagents for biochemical research.

Basic Information

Product Name	1-Bromo-4-Chloro-2-Fluoro-3-Methoxybenzene
CAS No.	943832-96-0
Molecular Formula	C7H5BrClFO
Molecular Weight	239.47 g/mol
Synonyms	4-Bromo-1-Chloro-2-Fluoro-5-Methoxybenzene; 3-Methoxy-2-Fluoro-4-Bromochlorobenzene; 2-Fluoro-3-Methoxy-4-Bromo-1-Chlorobenzene; Benzene, 1-bromo-4-chloro-2-fluoro-3-methoxy-; 943832-96-0; 4-Bromo-1-chloro-2-fluoro-5-methoxy-benzene
EINECS	Contact for details

Quality Control

Our 1-Bromo-4-Chloro-2-Fluoro-3-Methoxybenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Purity (GC)	≥97.0%
Melting Point	Contact for details
Heavy Metals	<10 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.