Description

4-Bromo-2-Fluoro-3-Methoxyphenylboronic Acid is a high-purity, multi-functional boronic acid derivative that serves as a critical building block in advanced organic synthesis. Its unique halogenated and methoxylated structure makes it an exceptionally versatile reagent for constructing complex molecular architectures. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, leveraging its halogenated phenyl ring for bioactivity.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as OLEDs and semiconductors, where its structure aids in tuning electronic properties.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized boronic acid-based ligands used in asymmetric catalysis.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and enzyme inhibition.
• Custom Fine Chemical Production: An essential building block for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for clients.

Basic Information

Product Name	4-Bromo-2-Fluoro-3-Methoxyphenylboronic Acid
CAS No.	943830-77-1
Molecular Formula	C7H7BBrFO3
Molecular Weight	247.85 g/mol
Synonyms	(4-Bromo-2-fluoro-3-methoxyphenyl)boronic acid; 4-Bromo-2-fluoro-3-methoxybenzeneboronic acid; B-(4-Bromo-2-fluoro-3-methoxyphenyl)boronic acid; Boronic acid, B-(4-bromo-2-fluoro-3-methoxyphenyl)-; 943830-77-1; 4-Br-2-F-3-MeO-PhB(OH)2
EINECS	Contact for details

Quality Control

Every batch of 4-Bromo-2-Fluoro-3-Methoxyphenylboronic Acid is manufactured and tested under a strict quality management system. We guarantee high chemical purity and lot-to-lot consistency suitable for demanding R&D and scale-up processes. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to ensure full traceability and compliance with your internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (argon or nitrogen) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.