Description

1,2-Methylenedioxy-3-Fluorobenzene is a high-purity fluorinated aromatic building block of significant interest in advanced organic synthesis. Its value lies in the unique reactivity imparted by the combined methylenedioxy and fluorine substituents, enabling precise molecular construction. This compound is primarily needed by research and development chemists and process scale-up teams in the pharmaceutical and agrochemical industries for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly those targeting the central nervous system.
• Agrochemical Synthesis: Used in the development of new-generation herbicides and pesticides, leveraging the fluorine atom for enhanced bioactivity and stability.
• Ligand and Catalyst Development: Serves as a backbone for creating specialized ligands used in asymmetric catalysis and material science.
• Fluorine Chemistry Research: An essential reagent for studying structure-activity relationships (SAR) and introducing fluorine into complex scaffolds.
• Fine Chemical Production: Employed in the multi-step synthesis of specialty chemicals and advanced materials.
• Reference Standard: Used as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	1,2-Methylenedioxy-3-Fluorobenzene
CAS No.	943830-74-8
Molecular Formula	C7H5FO2
Molecular Weight	140.11 g/mol
Synonyms	3-Fluoro-1,2-benzodioxole; 3-Fluoro-1,2-methylenedioxybenzene; 3-Fluorocatechol methylene ether; 3-Fluorobenzodioxole; 1,2-(Methylenedioxy)-3-fluorobenzene; 3-Fluoro-1,2-(methylenedioxy)benzene; 3-Fluoropyrocatechol methylene ether
EINECS	Contact for details

Quality Control

Our production of 1,2-Methylenedioxy-3-Fluorobenzene adheres to stringent in-process controls and final release testing to ensure batch-to-batch consistency and high purity. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We operate under a cGMP-compliant quality management system, and our facilities are prepared for audits to meet the rigorous standards of the pharmaceutical and fine chemical industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and oxidizing agents. Recommended storage temperature is 2-8°C for long-term stability, although the product is stable at controlled room temperature for shorter periods. Keep container tightly sealed when not in use to prevent moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.