Description

Bicyclo[2.2.1]Heptane, 2-Ethynyl- is a highly specialized organic building block featuring a rigid norbornane skeleton with a reactive terminal alkyne functional group. This unique structure makes it a critical intermediate for synthesizing advanced materials and complex pharmaceutical scaffolds, offering precise spatial control in molecular design. It is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and advanced polymer industries for applications in medicinal chemistry, ligand synthesis, and the creation of novel polymers with tailored properties.

Application

• Pharmaceutical Intermediate: A key synthon for constructing complex, three-dimensional molecular architectures in drug discovery, particularly for central nervous system (CNS) and antiviral targets.
• Agrochemical Synthesis: Used in the development of novel pesticides and herbicides where the norbornane core contributes to biological activity and environmental stability.
• Advanced Material Precursor: Serves as a monomer or cross-linking agent for high-performance polymers, resins, and specialty coatings with enhanced thermal and mechanical properties.
• Ligand and Catalyst Development: The alkyne group enables click chemistry (e.g., CuAAC, SPAAC) for facile conjugation, making it valuable for creating chelating ligands, catalysts, and bioconjugation probes.
• Academic and Industrial Research: A versatile tool for synthetic organic chemists exploring new reaction methodologies and constructing molecular machines or complex natural product analogs.
• Specialty Chemical Manufacturing: Employed in the production of flavors, fragrances, and electronic chemicals where precise stereochemistry is required.

Basic Information

Product Name	Bicyclo[2.2.1]Heptane, 2-Ethynyl-
CAS No.	942577-24-4
Molecular Formula	C9H10
Molecular Weight	118.18 g/mol
Synonyms	2-Ethynylbicyclo[2.2.1]heptane; 2-Ethynylnorbornane; Norbornane, 2-ethynyl-; 2-Ethynyl-2-norbornane; Bicyclo[2.2.1]hept-2-ylacetylene; 2-Norbornylacetylene
EINECS	Contact for details

Quality Control

Our Bicyclo[2.2.1]Heptane, 2-Ethynyl- is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, assay, and impurity profiles to support your R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound may be sensitive to prolonged exposure to air and moisture; for long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 95.0%
Assay (HPLC)	≥ 94.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.