Description

Methyl 2-(4-Bromo-3-Fluorophenyl)Acetate is a high-purity organic building block of significant importance in advanced chemical synthesis. This compound serves as a critical intermediate for the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily sought after by R&D chemists and process development scientists for constructing active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides and fungicides, leveraging the bioactivity of the halogenated phenyl moiety.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and transition metal complexes.
• Material Science Research: Employed in the synthesis of organic semiconductors and liquid crystals, where the bromo-fluoro substitution pattern can tune electronic properties.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and production under cGMP guidelines.

Basic Information

Product Name	Methyl 2-(4-Bromo-3-Fluorophenyl)Acetate
CAS No.	942282-41-9
Molecular Formula	C9H8BrFO2
Molecular Weight	247.06 g/mol
Synonyms	Methyl (4-Bromo-3-fluorophenyl)acetate; (4-Bromo-3-fluorophenyl)acetic acid methyl ester; 2-(4-Bromo-3-fluorophenyl)acetic acid methyl ester; Methyl 4'-bromo-3'-fluorophenylacetate; Acetic acid, 2-(4-bromo-3-fluorophenyl)-, methyl ester; Methyl α-(4-bromo-3-fluorophenyl)acetate
EINECS	Contact for details

Quality Control

Our production of Methyl 2-(4-Bromo-3-Fluorophenyl)Acetate adheres to stringent quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment supports compliance with REACH and other global regulatory frameworks essential for pharmaceutical and agrochemical supply chains.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.