Description

3-Chloro-5-(Trifluoromethyl)Phenylboronic Acid Pinacol Ester is a high-value, organoboron building block essential for modern synthetic chemistry. Its core value lies in enabling efficient cross-coupling reactions, such as the Suzuki-Miyaura reaction, to construct complex molecular architectures. This compound is critically needed by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing the biologically relevant trifluoromethyl and chloro-substituted phenyl motifs.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides where the specific halogen and fluorine pattern enhances bioactivity and environmental stability.
• Material Science Research: Serves as a monomer or building block for constructing organic electronic materials, such as OLEDs and semiconductors, via palladium-catalyzed polymerization.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized in the synthesis of molecular probes and tags for studying biological systems and diagnostic applications.
• Scale-up and Process Chemistry: Supplied in commercial quantities for process optimization and pilot-scale manufacturing of target molecules.

Basic Information

Product Name	3-Chloro-5-(Trifluoromethyl)Phenylboronic Acid Pinacol Ester
CAS No.	942069-65-0
Molecular Formula	C13H15BClF3O2
Molecular Weight	306.52 g/mol
Synonyms	[3-Chloro-5-(trifluoromethyl)phenyl]boronic acid pinacol ester; (3-Chloro-5-(trifluoromethyl)phenyl)boronic acid pinacol ester; Pinacol [3-Chloro-5-(trifluoromethyl)phenyl]boronate; 3-Chloro-5-trifluoromethylbenzeneboronic acid pinacol ester; B-[3-Chloro-5-(trifluoromethyl)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; Boronic acid, B-[3-chloro-5-(trifluoromethyl)phenyl]-, 1,1-dimethylethyl ester; 942069-65-0; 3-Chloro-5-(trifluoromethyl)phenylboronic acid neopentyl glycol ester (common alternative)
EINECS	Contact for details

Quality Control

Our 3-Chloro-5-(Trifluoromethyl)Phenylboronic Acid Pinacol Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC, to ensure high purity and lot-to-lot consistency suitable for demanding synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment. We support cGMP and ISO standards for pharmaceutical and industrial customers.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Typical 98-99%)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.