Description

5-Bromo-2-Fluoro-1,3-Phenylenediboronic Acid,Bispinacol is a high-purity, multi-functional boronic acid derivative and a key synthetic intermediate in modern organic chemistry. Its value lies in its dual boronic ester functionality, which enables efficient and selective cross-coupling reactions, such as the Suzuki-Miyaura reaction, for constructing complex aromatic scaffolds. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise molecular building blocks for drug discovery, ligand synthesis, and the development of organic electronic materials.

Application

• Pharmaceutical Intermediate: A critical building block for synthesizing active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing complex, halogenated biphenyl or heterobiaryl structures.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that require specific halogenated aromatic cores for enhanced bioactivity.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the development of organic semiconductors, conductive polymers, and metal-organic frameworks (MOFs) for electronic and sensing applications.
• Ligand and Catalyst Development: Employed in the synthesis of specialized bidentate ligands for transition metal catalysis, enabling more efficient and selective chemical transformations.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D labs for exploring new synthetic methodologies and creating libraries of novel aromatic compounds.

Basic Information

Product Name	5-Bromo-2-Fluoro-1,3-Phenylenediboronic Acid,Bispinacol
CAS No.	942069-49-0
Molecular Formula	C₁₈H₂₆BBrFO₄
Molecular Weight	407.12 g/mol
Synonyms	5-Bromo-2-fluoro-1,3-phenylenebis(boronic acid) pinacol ester; 1,3-Bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-5-bromo-2-fluorobenzene; 5-Bromo-2-fluoro-1,3-phenylene diboronic acid bis(pinacol) ester; 2-Fluoro-5-bromo-1,3-phenylenebis(boronic acid pinacol ester); 942069-49-0; 5-Br-2-F-1,3-Phenylenediboronic Acid Bispinacol Ester
EINECS	Contact for details

Quality Control

Our production of 5-Bromo-2-Fluoro-1,3-Phenylenediboronic Acid,Bispinacol adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including NMR, HPLC, and GC-MS to verify identity, potency, and impurity profiles. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.