Description

Meloxicam-D3 is a deuterium-labeled analog of the non-steroidal anti-inflammatory drug (NSAID) Meloxicam, specifically designed for use as an internal standard in quantitative analytical methods. This stable isotope-labeled compound is essential for ensuring the accuracy and reliability of mass spectrometry-based analyses, particularly in pharmacokinetic and bioequivalence studies. It is a critical tool for pharmaceutical research and development laboratories, contract research organizations (CROs), and regulatory testing facilities that require the highest level of precision in drug metabolism and quantification assays.

Application

• Primary use as an internal standard in Liquid Chromatography-Mass Spectrometry (LC-MS/MS) and Gas Chromatography-Mass Spectrometry (GC-MS) for the quantification of Meloxicam.
• Critical component in pharmacokinetic (PK) and bioanalytical studies to determine drug concentration in biological matrices like plasma, serum, and urine.
• Enabling technology for drug metabolism and disposition (DMPK) research, aiding in the understanding of Meloxicam's metabolic pathways.
• Used in bioequivalence testing for generic drug development, ensuring analytical method compliance with regulatory standards (e.g., FDA, EMA).
• Supporting clinical trial analysis by providing a stable reference for accurate patient sample measurement.
• Application in forensic and anti-doping analysis for the precise identification and quantification of Meloxicam.
• Essential for method development and validation in analytical laboratories to meet Good Laboratory Practice (GLP) guidelines.

Basic Information

Product Name	Meloxicam-D3
CAS No.	942047-63-4
Molecular Formula	C14H10D3N3O4S2
Molecular Weight	354.42 g/mol (approximate)
Synonyms	4-Hydroxy-2-methyl-N-(5-methyl-1,3-thiazol-2-yl)-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide-d3; [D3]-Meloxicam; Meloxicam (methyl-d3); Deuterated Meloxicam; Meloxicam Internal Standard; 2-Methyl-4-hydroxy-N-(5-methyl-2-thiazolyl)-2H-1,2-benzothiazine-3-carboxamide-1,1-dioxide-d3; UNII-7D8A6F32B8
EINECS	Contact for details

Quality Control

Every batch of our Meloxicam-D3 is manufactured and tested to meet the stringent requirements for stable isotope-labeled reference standards. Our products undergo rigorous quality testing, including advanced spectroscopic and chromatographic methods, to ensure high chemical purity, isotopic purity (deuterium incorporation), and exact concentration. Certificates of Analysis (COA) are provided with each shipment, detailing batch-specific results for identity, purity, and assay. We support compliance with GLP and cGMP standards for research and regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature, typically between 15-25°C (59-77°F). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent absorption of moisture. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Purity (HPLC)	≥ 98.0%
Isotopic Purity (MS)	≥ 99.0 atom % D (D3)
Chemical Purity	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.