Description

2-Bromo-n-tert-Butyl-5-Fluorobenzamide is a high-purity, advanced pharmaceutical intermediate characterized by its halogenated benzamide structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry research and development. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate halogenated aromatic motifs into complex molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Used in the development of new herbicides and pesticides, leveraging the biological activity of the fluorinated aromatic ring.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the creation of specialty polymers and advanced organic materials.
• Chemical Biology Probe: Employed in the design and synthesis of molecular probes for studying enzyme function and protein-ligand interactions.
• Custom Synthesis & Contract Manufacturing: A vital substrate for fine chemical manufacturers offering bespoke synthesis services to the life sciences sector.

Basic Information

Product Name	2-Bromo-n-tert-Butyl-5-Fluorobenzamide
CAS No.	941294-23-1
Molecular Formula	C11H13BrFNO
Molecular Weight	274.13 g/mol
Synonyms	2-Bromo-N-(tert-butyl)-5-fluorobenzamide; 5-Fluoro-2-bromo-N-tert-butylbenzamide; N-(tert-Butyl)-2-bromo-5-fluorobenzamide; 2-Bromo-5-fluoro-N-(1,1-dimethylethyl)benzamide; Benzamide, 2-bromo-N-(1,1-dimethylethyl)-5-fluoro-; 941294-23-1 (CAS); 2-Br-N-t-Bu-5-F-Benzamide
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-n-tert-Butyl-5-Fluorobenzamide is manufactured under a strict quality management system and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Our standard pharmaceutical intermediate grade meets rigorous in-house specifications. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting key parameters such as assay and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and handling properties. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.