Description

3-Bromo-n-Cyclopropyl-5-Nitrobenzamide is a high-purity, advanced pharmaceutical intermediate characterized by its unique halogenated and nitro-substituted benzamide structure. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to introduce specific functional groups for bioactivity screening and lead optimization.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammatory diseases, and oncology.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies due to the reactivity of the bromo and nitro groups for further functionalization.
• Agrochemical Development: Serves as a building block for creating novel herbicides, fungicides, or insecticides with specific modes of action.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity, complex intermediates.

Basic Information

Product Name	3-Bromo-n-Cyclopropyl-5-Nitrobenzamide
CAS No.	941294-17-3
Molecular Formula	C10H9BrN2O3
Molecular Weight	285.10 g/mol
Synonyms	3-Bromo-N-cyclopropyl-5-nitrobenzamide; Benzamide, 3-bromo-N-cyclopropyl-5-nitro-; 3-Bromo-5-nitro-N-cyclopropylbenzamide; N-Cyclopropyl-3-bromo-5-nitrobenzamide; 941294-17-3; 3-Br-N-CP-5-NO2-Benzamide
EINECS	Contact for details

Quality Control

Our 3-Bromo-n-Cyclopropyl-5-Nitrobenzamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and internal quality standards. Our commitment to traceability and documentation supports regulatory requirements for advanced intermediates in development pipelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.