Description

1-Benzyl-5-Iodoimidazole is a versatile halogenated imidazole derivative of significant interest in advanced organic synthesis. This compound serves as a crucial synthetic intermediate, valued for its reactive iodine substituent and the protective benzyl group, which enables selective functionalization. It is primarily utilized by researchers and manufacturers in the pharmaceutical and agrochemical industries for the development of novel active compounds and complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, particularly those targeting enzyme inhibition.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides due to its bioactive imidazole core.
• Ligand Synthesis: Serves as a precursor for creating specialized ligands used in catalysis and material science.
• Chemical Biology Probes: Employed in the design of molecular probes for studying biological processes and protein interactions.
• Cross-Coupling Reactions: The iodine atom makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to form complex biaryl structures.
• Heterocyclic Chemistry: Fundamental reagent for constructing more complex nitrogen-containing heterocycles through further ring formation or modification.

Basic Information

Product Name	1-Benzyl-5-Iodoimidazole
CAS No.	941286-76-6
Molecular Formula	C10H9IN2
Molecular Weight	284.10 g/mol
Synonyms	5-Iodo-1-benzylimidazole; 1-Benzyl-1H-imidazole, 5-iodo-; 1-Benzyl-5-iodo-1H-imidazole; 5-Iodo-1-benzyl-1H-imidazole; 1H-Imidazole, 5-iodo-1-(phenylmethyl)-
EINECS	Contact for details

Quality Control

Our 1-Benzyl-5-Iodoimidazole is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification and NMR for structural confirmation, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing specific results for purity, identity, and impurities is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.