Description

4,5-Bis(Dicyclohexylphosphino)-9,10A-Dihydro- 9,9-Dimethyl-8Ah-Xanthene is a specialized, high-value organophosphorus ligand with a rigid xanthene backbone. This compound matters for its exceptional ability to control stereoselectivity and enhance catalytic activity in transition metal-catalyzed cross-coupling reactions. It is primarily needed by R&D chemists and process engineers in the pharmaceutical, agrochemical, and advanced materials sectors for developing novel synthetic pathways and optimizing manufacturing processes.

Application

• Asymmetric Hydrogenation Catalysis: A key ligand for the enantioselective reduction of prochiral olefins, ketones, and imines in pharmaceutical intermediate synthesis.
• Cross-Coupling Reactions: Employed in Buchwald-Hartwig amination, Suzuki-Miyaura, and other C-C/C-N bond-forming reactions requiring high turnover numbers and selectivity.
• Homogeneous Catalyst Development: Serves as a privileged scaffold for constructing novel transition metal complexes (e.g., Pd, Rh, Ru) for fine chemical production.
• Pharmaceutical Process Chemistry: Used in the scalable synthesis of active pharmaceutical ingredients (APIs) where precise stereochemical control is critical.
• Agrochemical Synthesis: Facilitates the creation of complex, chiral molecules for novel herbicides, fungicides, and insecticides.
• Academic & Industrial Research: A valuable tool for methodological development in organic synthesis and catalysis science.

Basic Information

Product Name	4,5-Bis(Dicyclohexylphosphino)-9,10A-Dihydro- 9,9-Dimethyl-8Ah-Xanthene
CAS No.	940934-47-4
Molecular Formula	C41H58OP2
Molecular Weight	628.85 g/mol
Synonyms	4,5-Bis(dicyclohexylphosphino)-9,9-dimethyl-9,10-dihydro-8aH-xanthene; XantPhos-DC; Dihydroxantphos-DC; 9,9-Dimethyl-4,5-bis(dicyclohexylphosphino)-9,10-dihydro-8aH-xanthene; DC-XantPhos; Xantphos derivative with dicyclohexylphosphino groups; Bridged xanthene phosphine ligand; Contact for additional trade names.
EINECS	Contact for details

Quality Control

Every batch of our 4,5-Bis(Dicyclohexylphosphino)-9,10A-Dihydro- 9,9-Dimethyl-8Ah-Xanthene is produced and handled under a strict quality management system. We guarantee high purity and consistency, with specifications tailored for demanding catalytic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment to ensure traceability and support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store under an inert atmosphere (argon or nitrogen) at 2-8°C. This product is easily oxidized and moisture-sensitive; ensure containers are sealed immediately after use and kept in a cool, dry, and well-ventilated area.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.