Description

(R)-Carisbamate β-D-o-Glucuronide is a high-purity, synthetic reference standard and pharmaceutical intermediate. This compound is critical for analytical research, method development, and quality control processes in drug development and manufacturing. It is primarily utilized by pharmaceutical R&D laboratories, CROs, and manufacturers specializing in central nervous system (CNS) active pharmaceutical ingredients (APIs) and their metabolites.

Application

• Pharmaceutical Reference Standard: For the qualitative and quantitative analysis of Carisbamate and its metabolites in drug substance and drug product testing.
• Metabolite Identification & Profiling: Used in ADME (Absorption, Distribution, Metabolism, and Excretion) studies to understand the pharmacokinetic profile of Carisbamate.
• Analytical Method Development & Validation: Serves as a critical component for developing and validating HPLC, LC-MS, and other chromatographic methods.
• Impurity Characterization: Acts as a known impurity or degradation product standard to ensure API purity and compliance with ICH guidelines.
• Preclinical & Clinical Research: Employed in bioanalytical assays for measuring drug and metabolite levels in biological matrices during trials.
• GMP Manufacturing Support: Used for in-process control and release testing of Carisbamate API batches.

Basic Information

Product Name	(R)-Carisbamate β-D-o-Glucuronide
CAS No.	940279-83-4
Molecular Formula	C20H27NO11
Molecular Weight	457.43 g/mol
Synonyms	(R)-Carisbamate Glucuronide; (R)-2-O-Carbamoyl-1,2-ethanediol 1-β-D-Glucopyranosiduronic Acid; S-Licarbamate Glucuronide (stereospecific); Carisbamate Metabolite M9; (R)-1,2-Ethanediol, 2-(aminocarbonyl)-, 1-(β-D-glucopyranosiduronic acid); UNII-7Q1F4W8R4F; 940279-83-4; Carisbamate β-D-Glucuronide (R-enantiomer)
EINECS	Contact for details

Quality Control

Our (R)-Carisbamate β-D-o-Glucuronide is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, MS), to ensure it meets the stringent requirements for pharmaceutical reference standards. A detailed Certificate of Analysis (COA) providing batch-specific data is supplied with every order.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label or COA. Keep the container in a dry, cool, and well-ventilated area.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.