Description

(S)-Carisbamate β-D-o-Glucuronide is a high-purity, synthetic reference standard and pharmaceutical intermediate. This compound is critical for analytical method development, pharmacokinetic studies, and quality control in pharmaceutical research and manufacturing. It is primarily utilized by research institutions, contract research organizations (CROs), and pharmaceutical companies engaged in the development and production of advanced therapeutics.

Application

• Pharmaceutical Reference Standard: Used for the identification, assay, and impurity profiling of Carisbamate and related compounds in drug substances and products via HPLC, LC-MS, and other analytical techniques.
• Metabolite Studies: Serves as a critical standard for investigating the metabolism, pharmacokinetics, and bioavailability of Carisbamate in preclinical and clinical research.
• Process Development & Validation: Employed in the development and validation of synthetic routes and purification processes within Active Pharmaceutical Ingredient (API) manufacturing.
• Quality Control & Assurance: Essential for establishing and maintaining rigorous quality control protocols in GMP-compliant pharmaceutical production environments.
• Regulatory Submissions: Provides characterized material to support regulatory filings (e.g., IND, NDA) with agencies such as the FDA and EMA.

Basic Information

Product Name	(S)-Carisbamate β-D-o-Glucuronide
CAS No.	940279-82-3
Molecular Formula	C15H17NO9
Molecular Weight	355.30 g/mol
Synonyms	(S)-Carisbamate Glucuronide; (S)-RWJ-333369 glucuronide; (2S)-2-Hydroxy-2-phenylpropyl carbamate β-D-glucopyranosiduronic acid; Carisbamate metabolite; O-((S)-1-Carbamoyloxy-1-phenylpropan-2-yl) β-D-glucuronic acid
EINECS	Contact for details

Quality Control

Every batch of (S)-Carisbamate β-D-o-Glucuronide is manufactured and tested under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a dry, cool place. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.