Description

tert-Butyl 2-Chlorobenzylcarbamate is a specialized organic building block of significant importance in advanced chemical synthesis. This compound serves as a key protected intermediate, enabling the controlled introduction of the 2-chlorobenzylamine moiety into complex molecular architectures. It is primarily required by research and development chemists and process scale-up teams within the pharmaceutical and agrochemical industries for the production of active ingredients and novel compounds.

Application

• As a crucial protected amine intermediate in multi-step pharmaceutical synthesis, particularly for active pharmaceutical ingredients (APIs).
• In the research and development of novel agrochemicals, including herbicides and fungicides.
• For the synthesis of custom ligands and catalysts used in asymmetric catalysis and material science.
• As a building block in peptidomimetic and small molecule drug discovery programs.
• In the preparation of specialty fine chemicals and advanced materials requiring specific aromatic amine functionalities.

Basic Information

Product Name	tert-Butyl 2-Chlorobenzylcarbamate
CAS No.	940215-81-6
Molecular Formula	C12H16ClNO2
Molecular Weight	241.71 g/mol
Synonyms	Boc-2-Chlorobenzylamine; N-(tert-Butoxycarbonyl)-2-chlorobenzylamine; 2-Chlorobenzylcarbamic Acid tert-Butyl Ester; tert-Butyl N-[(2-Chlorophenyl)methyl]carbamate; N-Boc-2-chlorobenzylamine; (2-Chlorobenzyl)carbamic Acid 1,1-Dimethylethyl Ester; 1-Chloro-2-[[[(1,1-dimethylethoxy)carbonyl]amino]methyl]benzene
EINECS	Contact for details

Quality Control

Our tert-Butyl 2-Chlorobenzylcarbamate is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. The product undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.