Description

1-(2-Chloro-Thiazol-5-Ylmethyl)-Piperidin-4-Ol is a high-purity, advanced pharmaceutical intermediate characterized by its unique heterocyclic structure combining thiazole and piperidine moieties. This compound is of significant value for research and development in medicinal chemistry, particularly for creating novel active pharmaceutical ingredients (APIs) with targeted biological activity. It is primarily needed by pharmaceutical manufacturers, agrochemical R&D teams, and specialized fine chemical synthesis laboratories engaged in developing new therapeutic agents and crop protection products.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-infective therapeutic areas.
• Agrochemical Research: Serves as a precursor for developing new generation pesticides and herbicides, leveraging its heterocyclic scaffold.
• Medicinal Chemistry R&D: Used in structure-activity relationship (SAR) studies and library synthesis for hit-to-lead optimization in drug discovery programs.
• Fine Chemical Synthesis: Employed in custom synthesis and contract manufacturing for producing specialized, high-value chemical entities.
• Biochemical Tool Compound: Potential use in biochemical assays and as a pharmacological probe to study specific biological pathways.

Basic Information

Product Name	1-(2-Chloro-Thiazol-5-Ylmethyl)-Piperidin-4-Ol
CAS No.	939986-50-2
Molecular Formula	C9H13ClN2OS
Molecular Weight	232.73 g/mol
Synonyms	4-Piperidinol, 1-[(2-chloro-5-thiazolyl)methyl]-; 1-[(2-Chloro-1,3-thiazol-5-yl)methyl]piperidin-4-ol; 1-[(2-Chlorothiazol-5-yl)methyl]piperidin-4-ol; 939986-50-2; AKOS005258209; 1-(2-Chloro-thiazol-5-ylmethyl)-piperidin-4-ol; 1-(2-Chlorothiazol-5-ylmethyl)piperidin-4-ol
EINECS	Contact for details

Quality Control

Our 1-(2-Chloro-Thiazol-5-Ylmethyl)-Piperidin-4-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical and agrochemical R&D. Certificates of Analysis (COA) documenting purity, assay, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider under an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Any individual impurity ≤ 1.0%
Total Impurities	≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.