Description

3-[(4-Chloro-2-Pyrimidinyl)Oxy]-1-Piperidinecarboxylic Acid tert-Butyl Ester is a high-value pharmaceutical intermediate and chemical building block. This compound is critical for the synthesis of complex molecules, offering a protected piperidine scaffold and a reactive pyrimidine moiety for further functionalization. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, particularly in kinase inhibitor research.
• Agrochemical Research: Used in the development of novel herbicides and pesticides due to its heterocyclic structure.
• Chemical Synthesis: Serves as a versatile precursor for introducing the 4-chloro-2-pyrimidinyloxy group into more complex molecular architectures.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies and lead optimization processes.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs producing specialized compounds for clients.
• Academic Research: Used in university and institutional labs for methodological development and exploring new chemical reactions.

Basic Information

Product Name	3-[(4-Chloro-2-Pyrimidinyl)Oxy]-1-Piperidinecarboxylic Acid tert-Butyl Ester
CAS No.	939986-47-7
Molecular Formula	C14H18ClN3O3
Molecular Weight	311.76 g/mol
Synonyms	tert-Butyl 3-[(4-chloropyrimidin-2-yl)oxy]piperidine-1-carboxylate; 1-Boc-3-[(4-chloro-2-pyrimidinyl)oxy]piperidine; 1-(tert-Butoxycarbonyl)-3-[(4-chloro-2-pyrimidinyl)oxy]piperidine; 3-(4-Chloro-pyrimidin-2-yloxy)-piperidine-1-carboxylic acid tert-butyl ester; Piperidine-1-carboxylic acid, 3-[(4-chloro-2-pyrimidinyl)oxy]-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our production of 3-[(4-Chloro-2-Pyrimidinyl)Oxy]-1-Piperidinecarboxylic Acid tert-Butyl Ester adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for research and development applications. All materials are accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support compliance with cGMP standards where required for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.